When a Cardiac Drug Becomes a Lung Treatment: Tadalafil's Expanding Role in Respiratory Medicine
Originally developed to address erectile dysfunction, tadalafil has emerged as a clinically significant treatment for pulmonary arterial hypertension and other serious cardiopulmonary conditions. This article examines the pharmacological science behind this expansion, reviews the clinical evidence, and explores what it means for the millions of Americans living with complex lung and heart disease.